Sionna Therapeutics, Inc. Investigation - SION

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Sionna Therapeutics, Inc. (NASDAQ: SION)

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Certification of Plaintiff Pursuant to Federal Securities Laws

I, duly certify and say, as to the claims asserted under the federal securities laws, that:

1.I have reviewed a complaint filed in the action.

2.I did not purchase the security that is the subject of this action at the direction of plaintiff's counsel or in order to participate in this action.

3.I am willing to serve as a representative party on behalf of the class, including providing testimony at deposition and trial, if necessary.

4.My transaction(s) in which are the subject of this litigation during the class period set forth in the complaint are set forth in the chart attached hereto.

5.Within the last 3 years,

6.I will not accept any payment for serving as a representative party on behalf of the class beyond the Plaintiff's pro rata share of any recovery, except as ordered or approved by the court, including any award for reasonable costs and expenses (including lost wages) directly relating to the representation of the class.

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Signed pursuant to California Civil Code Section 1633.1, et seq. - and the Uniform Electronic Transactions Act as adopted by the various states and territories of the United States.

By your signature above, you confirm that have retained Levi & Korsinsky, LLP to represent you and the shareholder class as a lead plaintiff in the pending class action against Sionna Therapeutics, Inc. This representation will be on a contingency basis, meaning that Levi & Korsinsky will advance all expenses in the litigation and will only seek compensation and/or reimbursement of expenses if the firm obtains a recovery. Regardless of the result, we will never ask you to directly pay for any attorneys’ fees, expenses, or costs. Should we obtain a favorable result, we may ask the court to award us compensation and reimbursement of expenses to be paid by the defendants or as a portion of any class recovery. In exchange for our representation, you agree to cooperate as our client by providing, for example, relevant documents and deposition testimony, if necessary. During the course of this litigation, we may employ and/or work with other law firms, experts, and third-parties to successfully prosecute this action. If you are not appointed as the lead plaintiff or Levi & Korsinsky is not appointed as lead counsel, we will notify you of such decision at which time this representation will end unless otherwise extended by you and the firm. We look forward to working with you towards a successful resolution of this action.

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Sionna Therapeutics, Inc Investigation Details

Sionna Therapeutics shares collapsed approximately 92% after the Company disclosed that its Phase 2a PreciSION CF trial of SION-719 failed to achieve its key activity endpoint and that it would not advance the candidate as an add-on therapy. According to the Company's disclosure, SION-719 -- administered on top of standard of care -- produced a placebo-adjusted sweat chloride change of -1.0 mmol/L, with a p-value of 0.7. Sionna stated it would not advance SION-719 as an add-on therapy. The decline did not follow an apparent liquidity shortfall: Sionna reported approximately $268.3 million in cash, cash equivalents and marketable securities as of June 30, 2026, and a second-quarter net loss of $29.9 million. Sionna's NBD1 stabilizer programs are central to its cystic fibrosis pipeline. The Company's FY2025 Form 10-K stated that it was "substantially dependent on the success of at least one of our nucleotide binding domain 1 ('NBD1') stabilizers." The investigation concerns whether SION investors received adequate disclosure regarding the Company’s reliance on its NBD1 stabilizer programs and the risks associated with the SION-719 program.

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