The table below lists insider purchases and sales reported by company officers, directors, and major shareholders during the last 12 months.
DATE INSIDER |
INSIDER | TYPE | SHARES | PRICE | SHARES PRICE VALUE |
|---|---|---|---|---|---|
Jun 27, 2025 Thompson Peter A. |
Thompson Peter A.
|
Sell |
1,176,332 | $4.16 | 1,176,332 $4.16 $4,891,894 |
Jun 27, 2025 ORBIMED ADVISORS LLC |
ORBIMED ADVISORS LLC
|
Sell |
1,176,332 | $4.16 | 1,176,332 $4.16 $4,891,894 |
May 06, 2024 Jones William Benton |
Jones William Benton
See Remarks
|
Buy |
19,357 | $0.00 | 19,357 $0.00 $12,201 |
May 06, 2024 Jones William Benton |
Jones William Benton
See Remarks
|
Buy |
20,000 | $1.73 | 20,000 $1.73 $34,624 |
May 06, 2024 Thompson Peter A. |
Thompson Peter A.
|
Buy |
1,397,684 | $0.00 | 1,397,684 $0.00 $0 |
May 06, 2024 Thompson Peter A. |
Thompson Peter A.
|
Buy |
1,444,085 | $1.73 | 1,444,085 $1.73 $0 |
May 06, 2024 ORBIMED ADVISORS LLC |
ORBIMED ADVISORS LLC
|
Buy |
1,397,684 | $0.00 | 1,397,684 $0.00 $0 |
May 06, 2024 ORBIMED ADVISORS LLC |
ORBIMED ADVISORS LLC
|
Buy |
1,444,085 | $1.73 | 1,444,085 $1.73 $0 |
May 06, 2024 MILLER RICHARD A MD |
MILLER RICHARD A MD
President and CEO
|
Buy |
559,073 | $0.00 | 559,073 $0.00 $352,384 |
May 06, 2024 MILLER RICHARD A MD |
MILLER RICHARD A MD
President and CEO
|
Buy |
577,634 | $1.73 | 577,634 $1.73 $1,000,000 |
May 15, 2023 Grais Linda S |
Grais Linda S
|
Buy |
10,000 | $2.45 | 10,000 $2.45 $24,500 |
Dec 20, 2022 Jones William Benton |
Jones William Benton
See Remarks
|
Buy |
20,000 | $0.79 | 20,000 $0.79 $15,800 |
Dec 14, 2022 LEA LEIV |
LEA LEIV
CFO
|
Buy |
4,000 | $0.84 | 4,000 $0.84 $3,364 |
Dec 14, 2022 MILLER RICHARD A MD |
MILLER RICHARD A MD
President and CEO
|
Buy |
10,000 | $0.78 | 10,000 $0.78 $7,812 |
Dec 13, 2022 MILLER RICHARD A MD |
MILLER RICHARD A MD
President and CEO
|
Buy |
50,000 | $0.74 | 50,000 $0.74 $37,015 |
Dec 13, 2022 LEA LEIV |
LEA LEIV
CFO
|
Buy |
30,000 | $0.74 | 30,000 $0.74 $22,275 |
Sep 28, 2022 MILLER RICHARD A MD |
MILLER RICHARD A MD
President and CEO
|
Buy |
25,000 | $0.76 | 25,000 $0.76 $19,070 |
Sep 20, 2022 MILLER RICHARD A MD |
MILLER RICHARD A MD
President and CEO
|
Buy |
12,300 | $0.81 | 12,300 $0.81 $9,964 |
Sep 20, 2022 MILLER RICHARD A MD |
MILLER RICHARD A MD
President and CEO
|
Buy |
2,700 | $0.82 | 2,700 $0.82 $2,214 |
Sep 20, 2022 MILLER RICHARD A MD |
MILLER RICHARD A MD
President and CEO
|
Buy |
5,000 | $0.82 | 5,000 $0.82 $4,075 |
Jun 27, 2022 MILLER RICHARD A MD |
MILLER RICHARD A MD
President and CEO
|
Buy |
5,000 | $1.00 | 5,000 $1.00 $4,985 |
Jun 24, 2022 MILLER RICHARD A MD |
MILLER RICHARD A MD
President and CEO
|
Buy |
5,000 | $1.03 | 5,000 $1.03 $5,150 |
Jun 06, 2022 MILLER RICHARD A MD |
MILLER RICHARD A MD
President and CEO
|
Buy |
890 | $1.01 | 890 $1.01 $899 |
Jun 02, 2022 MILLER RICHARD A MD |
MILLER RICHARD A MD
President and CEO
|
Buy |
4,830 | $0.98 | 4,830 $0.98 $4,733 |
Jun 02, 2022 MILLER RICHARD A MD |
MILLER RICHARD A MD
President and CEO
|
Buy |
170 | $0.97 | 170 $0.97 $165 |
Mar 17, 2022 LEA LEIV |
LEA LEIV
CFO
|
Buy |
13,878 | $1.65 | 13,878 $1.65 $22,899 |
Mar 17, 2022 MILLER RICHARD A MD |
MILLER RICHARD A MD
President and CEO
|
Buy |
5,000 | $1.59 | 5,000 $1.59 $7,950 |
Mar 16, 2022 LEA LEIV |
LEA LEIV
CFO
|
Buy |
35,160 | $1.54 | 35,160 $1.54 $54,146 |
Mar 15, 2022 MILLER RICHARD A MD |
MILLER RICHARD A MD
President and CEO
|
Buy |
25,000 | $1.47 | 25,000 $1.47 $36,650 |
Oct 01, 2021 EcoR1 Capital, LLC |
EcoR1 Capital, LLC
|
Sell |
2,000,000 | $4.96 | 2,000,000 $4.96 $9,928,800 |
Sep 30, 2021 EcoR1 Capital, LLC |
EcoR1 Capital, LLC
|
Sell |
3,000,000 | $5.04 | 3,000,000 $5.04 $15,131,100 |
Sep 20, 2021 Thompson Peter A. |
Thompson Peter A.
|
Sell |
1,109,644 | $6.09 | 1,109,644 $6.09 $6,757,732 |
Sep 20, 2021 ORBIMED ADVISORS LLC |
ORBIMED ADVISORS LLC
|
Sell |
1,109,644 | $6.09 | 1,109,644 $6.09 $6,757,732 |
Aug 20, 2021 MILLER RICHARD A MD |
MILLER RICHARD A MD
President and CEO
|
Buy |
10,000 | $1.93 | 10,000 $1.93 $19,254 |
May 04, 2021 MILLER RICHARD A MD |
MILLER RICHARD A MD
President and CEO
|
Buy |
35,714 | $2.80 | 35,714 $2.80 $99,999 |
Feb 17, 2021 Thompson Peter A. |
Thompson Peter A.
|
Buy |
1,285,714 | $3.50 | 1,285,714 $3.50 $4,499,999 |
Feb 17, 2021 MILLER RICHARD A MD |
MILLER RICHARD A MD
President and CEO
|
Buy |
100,000 | $3.50 | 100,000 $3.50 $350,000 |
Feb 17, 2021 ORBIMED ADVISORS LLC |
ORBIMED ADVISORS LLC
|
Buy |
1,285,714 | $3.50 | 1,285,714 $3.50 $4,499,999 |
Jul 08, 2020 Novo Holdings A/S |
Novo Holdings A/S
|
Sell |
741,440 | $5.37 | 741,440 $5.37 $3,985,166 |
Jul 07, 2020 Novo Holdings A/S |
Novo Holdings A/S
|
Sell |
796,622 | $5.25 | 796,622 $5.25 $4,183,381 |
Nov 13, 2019 MILLER RICHARD A MD |
MILLER RICHARD A MD
President and CEO
|
Buy |
14,736 | $3.00 | 14,736 $3.00 $44,240 |
Nov 12, 2019 MILLER RICHARD A MD |
MILLER RICHARD A MD
President and CEO
|
Buy |
272 | $2.90 | 272 $2.90 $789 |
Aug 07, 2019 MILLER RICHARD A MD |
MILLER RICHARD A MD
President and CEO
|
Buy |
2,500 | $3.54 | 2,500 $3.54 $8,850 |
Aug 06, 2019 ORBIMED ADVISORS LLC |
ORBIMED ADVISORS LLC
|
Buy |
142,656 | $3.51 | 142,656 $3.51 $500,723 |
Aug 06, 2019 MILLER RICHARD A MD |
MILLER RICHARD A MD
President and CEO
|
Buy |
5,000 | $3.58 | 5,000 $3.58 $17,875 |
Aug 06, 2019 Thompson Peter A. |
Thompson Peter A.
|
Buy |
142,656 | $3.51 | 142,656 $3.51 $500,723 |
Jul 25, 2019 Novo Holdings A/S |
Novo Holdings A/S
|
Sell |
1,400,000 | $4.00 | 1,400,000 $4.00 $5,600,000 |
Jul 24, 2019 Novo Holdings A/S |
Novo Holdings A/S
|
Sell |
53,240 | $5.01 | 53,240 $5.01 $266,711 |
Jul 23, 2019 Novo Holdings A/S |
Novo Holdings A/S
|
Sell |
39,716 | $5.32 | 39,716 $5.32 $211,134 |
Jul 01, 2019 Thompson Peter A. |
Thompson Peter A.
|
Buy |
59,243 | $3.91 | 59,243 $3.91 $231,640 |
Jul 01, 2019 ORBIMED ADVISORS LLC |
ORBIMED ADVISORS LLC
|
Buy |
59,243 | $3.91 | 59,243 $3.91 $231,640 |
Jun 28, 2019 ORBIMED ADVISORS LLC |
ORBIMED ADVISORS LLC
|
Buy |
565,178 | $3.72 | 565,178 $3.72 $2,102,462 |
Jun 28, 2019 Thompson Peter A. |
Thompson Peter A.
|
Buy |
565,178 | $3.72 | 565,178 $3.72 $2,102,462 |
Jun 27, 2019 Thompson Peter A. |
Thompson Peter A.
|
Buy |
32,923 | $3.34 | 32,923 $3.34 $109,963 |
Jun 27, 2019 ORBIMED ADVISORS LLC |
ORBIMED ADVISORS LLC
|
Buy |
32,923 | $3.34 | 32,923 $3.34 $109,963 |
Jun 14, 2019 MILLER RICHARD A MD |
MILLER RICHARD A MD
President and CEO
|
Buy |
11,657 | $3.40 | 11,657 $3.40 $39,666 |
Jun 13, 2019 MILLER RICHARD A MD |
MILLER RICHARD A MD
President and CEO
|
Buy |
343 | $3.52 | 343 $3.52 $1,207 |
Jun 11, 2019 MILLER RICHARD A MD |
MILLER RICHARD A MD
President and CEO
|
Buy |
6,000 | $3.67 | 6,000 $3.67 $22,020 |
Jun 07, 2019 MILLER RICHARD A MD |
MILLER RICHARD A MD
President and CEO
|
Buy |
9,212 | $3.37 | 9,212 $3.37 $31,019 |
Jun 07, 2019 LEA LEIV |
LEA LEIV
CFO
|
Buy |
10,000 | $3.38 | 10,000 $3.38 $33,800 |
Jun 06, 2019 LEA LEIV |
LEA LEIV
CFO
|
Buy |
15,500 | $3.56 | 15,500 $3.56 $55,180 |
Dec 27, 2018 MILLER RICHARD A MD |
MILLER RICHARD A MD
President and CEO
|
Buy |
20,000 | $3.29 | 20,000 $3.29 $65,884 |
Dec 21, 2018 LEA LEIV |
LEA LEIV
CFO
|
Buy |
24,700 | $4.15 | 24,700 $4.15 $102,409 |
Dec 20, 2018 MILLER RICHARD A MD |
MILLER RICHARD A MD
President and CEO
|
Buy |
5,000 | $4.39 | 5,000 $4.39 $21,950 |
Dec 20, 2018 MILLER RICHARD A MD |
MILLER RICHARD A MD
President and CEO
|
Buy |
5,000 | $4.40 | 5,000 $4.40 $22,000 |
Dec 06, 2018 MILLER RICHARD A MD |
MILLER RICHARD A MD
President and CEO
|
Buy |
5,000 | $5.99 | 5,000 $5.99 $29,934 |
Dec 04, 2018 MILLER RICHARD A MD |
MILLER RICHARD A MD
President and CEO
|
Buy |
1,502 | $5.95 | 1,502 $5.95 $8,937 |
Mar 12, 2018 ADAMS STREET PARTNERS LLC |
ADAMS STREET PARTNERS LLC
|
Buy |
236,128 | $8.50 | 236,128 $8.50 $2,007,088 |
Mar 12, 2018 ORBIMED ADVISORS LLC |
ORBIMED ADVISORS LLC
|
Buy |
588,235 | $8.50 | 588,235 $8.50 $4,999,998 |
Mar 12, 2018 MILLER RICHARD A MD |
MILLER RICHARD A MD
President and CEO
|
Buy |
100,000 | $8.50 | 100,000 $8.50 $850,000 |
Mar 12, 2018 Thompson Peter A. |
Thompson Peter A.
|
Buy |
588,235 | $8.50 | 588,235 $8.50 $4,999,998 |
Mar 12, 2018 ADAMS STREET PARTNERS LLC |
ADAMS STREET PARTNERS LLC
|
Buy |
69,864 | $8.50 | 69,864 $8.50 $593,844 |
Mar 12, 2018 Gould Terry P |
Gould Terry P
|
Buy |
87,668 | $8.50 | 87,668 $8.50 $745,178 |
Mar 12, 2018 Novo Holdings A/S |
Novo Holdings A/S
|
Buy |
1,176,470 | $8.50 | 1,176,470 $8.50 $9,999,995 |
Mar 12, 2018 ADAMS STREET PARTNERS LLC |
ADAMS STREET PARTNERS LLC
|
Buy |
67,769 | $8.50 | 67,769 $8.50 $576,037 |
Mar 12, 2018 ADAMS STREET PARTNERS LLC |
ADAMS STREET PARTNERS LLC
|
Buy |
87,668 | $8.50 | 87,668 $8.50 $745,178 |
Mar 12, 2018 ADAMS STREET PARTNERS LLC |
ADAMS STREET PARTNERS LLC
|
Buy |
126,806 | $8.50 | 126,806 $8.50 $1,077,851 |
Mar 12, 2018 Gould Terry P |
Gould Terry P
|
Buy |
69,864 | $8.50 | 69,864 $8.50 $593,844 |
Mar 12, 2018 Gould Terry P |
Gould Terry P
|
Buy |
236,128 | $8.50 | 236,128 $8.50 $2,007,088 |
Mar 12, 2018 Gould Terry P |
Gould Terry P
|
Buy |
67,769 | $8.50 | 67,769 $8.50 $576,037 |
Mar 12, 2018 Gould Terry P |
Gould Terry P
|
Buy |
126,806 | $8.50 | 126,806 $8.50 $1,077,851 |
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