The table below lists insider purchases and sales reported by company officers, directors, and major shareholders during the last 12 months.
DATE INSIDER |
INSIDER | TYPE | SHARES | PRICE | SHARES PRICE VALUE |
|---|---|---|---|---|---|
Aug 26, 2025 Russell Alan J |
Russell Alan J
Chief Scientific Officer
|
Sell |
100,000 | $14.60 | 100,000 $14.60 $1,459,760 |
Aug 12, 2025 Donovan Joanne M. |
Donovan Joanne M.
CMO
|
Sell |
2,862 | $13.39 | 2,862 $13.39 $38,329 |
Aug 12, 2025 Carruthers R Michael |
Carruthers R Michael
CFO
|
Sell |
1,428 | $13.39 | 1,428 $13.39 $19,124 |
Aug 12, 2025 KOCH KEVIN |
KOCH KEVIN
President and CEO
|
Sell |
7,972 | $13.39 | 7,972 $13.39 $106,764 |
Aug 12, 2025 Russell Alan J |
Russell Alan J
Chief Scientific Officer
|
Sell |
1,907 | $13.39 | 1,907 $13.39 $25,539 |
Aug 12, 2025 MOORE JOHN R |
MOORE JOHN R
General Counsel
|
Sell |
2,098 | $13.39 | 2,098 $13.39 $28,097 |
Aug 12, 2025 Derakhshan Behrad |
Derakhshan Behrad
CBO
|
Sell |
2,491 | $13.39 | 2,491 $13.39 $33,360 |
May 02, 2025 Donovan Joanne M. |
Donovan Joanne M.
CMO
|
Sell |
5,187 | $16.45 | 5,187 $16.45 $85,348 |
May 02, 2025 Carruthers R Michael |
Carruthers R Michael
CFO
|
Sell |
1,314 | $16.45 | 1,314 $16.45 $21,621 |
May 02, 2025 KOCH KEVIN |
KOCH KEVIN
President and CEO
|
Sell |
4,276 | $16.45 | 4,276 $16.45 $70,358 |
May 02, 2025 Russell Alan J |
Russell Alan J
Chief Scientific Officer
|
Sell |
1,551 | $16.45 | 1,551 $16.45 $25,520 |
May 02, 2025 MOORE JOHN R |
MOORE JOHN R
General Counsel
|
Sell |
1,930 | $16.45 | 1,930 $16.45 $31,757 |
May 02, 2025 Derakhshan Behrad |
Derakhshan Behrad
CBO
|
Sell |
1,691 | $16.45 | 1,691 $16.45 $27,824 |
Apr 03, 2025 ORBIMED ADVISORS LLC |
ORBIMED ADVISORS LLC
|
Buy |
372,578 | $20.13 | 372,578 $20.13 $7,499,995 |
Apr 03, 2025 ORBIMED ADVISORS LLC |
ORBIMED ADVISORS LLC
|
Buy |
124,193 | $20.13 | 124,193 $20.13 $2,500,005 |
Apr 03, 2025 Thompson Peter A. |
Thompson Peter A.
|
Buy |
372,578 | $20.13 | 372,578 $20.13 $7,499,995 |
Apr 03, 2025 Thompson Peter A. |
Thompson Peter A.
|
Buy |
124,193 | $20.13 | 124,193 $20.13 $2,500,005 |
Mar 07, 2025 KOCH KEVIN |
KOCH KEVIN
President and CEO
|
Sell |
100 | $30.00 | 100 $30.00 $3,000 |
Jan 28, 2025 Donovan Joanne M. |
Donovan Joanne M.
CMO
|
Sell |
25,000 | $27.63 | 25,000 $27.63 $690,658 |
Dec 30, 2024 Russell Alan J |
Russell Alan J
Chief Scientific Officer
|
Sell |
100,000 | $27.37 | 100,000 $27.37 $2,737,470 |
Dec 24, 2024 Semigran Marc |
Semigran Marc
Chief Development Officer
|
Sell |
27,980 | $29.66 | 27,980 $29.66 $829,906 |
Dec 24, 2024 Semigran Marc |
Semigran Marc
Chief Development Officer
|
Sell |
1,729 | $30.08 | 1,729 $30.08 $52,009 |
Sep 23, 2024 MOORE JOHN R |
MOORE JOHN R
General Counsel
|
Sell |
20,922 | $27.63 | 20,922 $27.63 $578,064 |
Sep 20, 2024 Donovan Joanne M. |
Donovan Joanne M.
CMO
|
Sell |
7,162 | $28.29 | 7,162 $28.29 $202,603 |
Sep 20, 2024 Carruthers R Michael |
Carruthers R Michael
CFO
|
Sell |
46,068 | $28.59 | 46,068 $28.59 $1,316,909 |
Sep 20, 2024 Carruthers R Michael |
Carruthers R Michael
CFO
|
Sell |
4,064 | $28.59 | 4,064 $28.59 $116,174 |
Sep 20, 2024 Carruthers R Michael |
Carruthers R Michael
CFO
|
Sell |
24,960 | $28.59 | 24,960 $28.59 $713,512 |
Sep 20, 2024 Carruthers R Michael |
Carruthers R Michael
CFO
|
Sell |
50,000 | $28.55 | 50,000 $28.55 $1,427,385 |
Sep 20, 2024 Russell Alan J |
Russell Alan J
Chief Scientific Officer
|
Sell |
74,185 | $28.25 | 74,185 $28.25 $2,096,053 |
Sep 20, 2024 Russell Alan J |
Russell Alan J
Chief Scientific Officer
|
Sell |
815 | $29.51 | 815 $29.51 $24,049 |
Sep 20, 2024 MOORE JOHN R |
MOORE JOHN R
General Counsel
|
Sell |
50,000 | $28.37 | 50,000 $28.37 $1,418,510 |
Sep 20, 2024 Derakhshan Behrad |
Derakhshan Behrad
CBO
|
Sell |
42,068 | $29.03 | 42,068 $29.03 $1,221,133 |
May 02, 2024 Donovan Joanne M. |
Donovan Joanne M.
CMO
|
Sell |
3,682 | $18.91 | 3,682 $18.91 $69,627 |
May 02, 2024 Carruthers R Michael |
Carruthers R Michael
CFO
|
Sell |
2,157 | $18.91 | 2,157 $18.91 $40,789 |
May 02, 2024 KOCH KEVIN |
KOCH KEVIN
President and CEO
|
Sell |
3,152 | $18.91 | 3,152 $18.91 $59,604 |
May 02, 2024 Russell Alan J |
Russell Alan J
Chief Scientific Officer
|
Sell |
1,576 | $18.91 | 1,576 $18.91 $29,802 |
May 02, 2024 MOORE JOHN R |
MOORE JOHN R
General Counsel
|
Sell |
1,956 | $18.91 | 1,956 $18.91 $36,988 |
May 02, 2024 Derakhshan Behrad |
Derakhshan Behrad
CBO
|
Sell |
1,718 | $18.91 | 1,718 $18.91 $32,487 |
Feb 09, 2024 MOORE JOHN R |
MOORE JOHN R
General Counsel
|
Sell |
8,029 | $20.01 | 8,029 $20.01 $160,657 |
Feb 09, 2024 Derakhshan Behrad |
Derakhshan Behrad
CBO
|
Sell |
4,800 | $20.04 | 4,800 $20.04 $96,209 |
Feb 08, 2024 MOORE JOHN R |
MOORE JOHN R
General Counsel
|
Sell |
3,813 | $20.01 | 3,813 $20.01 $76,285 |
Feb 08, 2024 Derakhshan Behrad |
Derakhshan Behrad
CBO
|
Sell |
4,600 | $20.01 | 4,600 $20.01 $92,049 |
Feb 07, 2024 MOORE JOHN R |
MOORE JOHN R
General Counsel
|
Sell |
17,993 | $20.00 | 17,993 $20.00 $359,864 |
Feb 07, 2024 Derakhshan Behrad |
Derakhshan Behrad
CBO
|
Sell |
600 | $20.00 | 600 $20.00 $12,000 |
Jan 23, 2024 ORBIMED ADVISORS LLC |
ORBIMED ADVISORS LLC
|
Buy |
454,545 | $11.00 | 454,545 $11.00 $4,999,995 |
Jan 23, 2024 Thompson Peter A. |
Thompson Peter A.
|
Buy |
454,545 | $11.00 | 454,545 $11.00 $4,999,995 |
Jan 23, 2024 Carruthers R Michael |
Carruthers R Michael
CFO
|
Sell |
90,000 | $15.78 | 90,000 $15.78 $1,419,759 |
Dec 27, 2023 MOORE JOHN R |
MOORE JOHN R
General Counsel
|
Sell |
8,497 | $10.50 | 8,497 $10.50 $89,219 |
Dec 26, 2023 Fox Jonathan C |
Fox Jonathan C
|
Buy |
10,857 | $9.30 | 10,857 $9.30 $100,958 |
Dec 26, 2023 Russell Alan J |
Russell Alan J
Chief Scientific Officer
|
Sell |
172,585 | $9.33 | 172,585 $9.33 $1,610,097 |
May 02, 2023 Donovan Joanne M. |
Donovan Joanne M.
CMO
|
Sell |
3,254 | $8.90 | 3,254 $8.90 $28,977 |
May 02, 2023 Carruthers R Michael |
Carruthers R Michael
CFO
|
Sell |
1,336 | $8.90 | 1,336 $8.90 $11,897 |
May 02, 2023 KOCH KEVIN |
KOCH KEVIN
President and CEO
|
Sell |
3,203 | $8.90 | 3,203 $8.90 $28,522 |
May 02, 2023 Russell Alan J |
Russell Alan J
Chief Scientific Officer
|
Sell |
1,602 | $8.90 | 1,602 $8.90 $14,266 |
May 02, 2023 MOORE JOHN R |
MOORE JOHN R
General Counsel
|
Sell |
1,897 | $8.90 | 1,897 $8.90 $16,893 |
May 02, 2023 Derakhshan Behrad |
Derakhshan Behrad
CBO
|
Sell |
1,747 | $8.90 | 1,747 $8.90 $15,557 |
Oct 03, 2022 MOORE JOHN R |
MOORE JOHN R
General Counsel
|
Sell |
4,730 | $9.76 | 4,730 $9.76 $46,155 |
Sep 16, 2022 ORBIMED ADVISORS LLC |
ORBIMED ADVISORS LLC
|
Buy |
484,496 | $10.32 | 484,496 $10.32 $4,999,999 |
Sep 16, 2022 Thompson Peter A. |
Thompson Peter A.
|
Buy |
484,496 | $10.32 | 484,496 $10.32 $4,999,999 |
Sep 14, 2022 Novo Holdings A/S |
Novo Holdings A/S
|
Buy |
484,496 | $10.32 | 484,496 $10.32 $4,999,999 |
Sep 06, 2022 MOORE JOHN R |
MOORE JOHN R
General Counsel
|
Sell |
2,379 | $10.83 | 2,379 $10.83 $25,756 |
Sep 06, 2022 MOORE JOHN R |
MOORE JOHN R
General Counsel
|
Sell |
2,351 | $10.99 | 2,351 $10.99 $25,842 |
Jul 06, 2022 MOORE JOHN R |
MOORE JOHN R
General Counsel
|
Sell |
1,046 | $8.54 | 1,046 $8.54 $8,928 |
Jul 05, 2022 MOORE JOHN R |
MOORE JOHN R
General Counsel
|
Sell |
8,186 | $8.35 | 8,186 $8.35 $68,329 |
Jun 21, 2022 MOORE JOHN R |
MOORE JOHN R
General Counsel
|
Sell |
31,078 | $7.29 | 31,078 $7.29 $226,695 |
Jun 17, 2022 MOORE JOHN R |
MOORE JOHN R
General Counsel
|
Sell |
22,127 | $6.62 | 22,127 $6.62 $146,434 |
Jun 16, 2022 MOORE JOHN R |
MOORE JOHN R
General Counsel
|
Sell |
14,722 | $6.17 | 14,722 $6.17 $90,805 |
Jun 15, 2022 MOORE JOHN R |
MOORE JOHN R
General Counsel
|
Sell |
585 | $6.11 | 585 $6.11 $3,575 |
Jun 15, 2022 MOORE JOHN R |
MOORE JOHN R
General Counsel
|
Sell |
18,075 | $6.11 | 18,075 $6.11 $110,445 |
Jun 14, 2022 MOORE JOHN R |
MOORE JOHN R
General Counsel
|
Sell |
3,628 | $6.02 | 3,628 $6.02 $21,855 |
Jun 13, 2022 MOORE JOHN R |
MOORE JOHN R
General Counsel
|
Sell |
4,093 | $6.01 | 4,093 $6.01 $24,582 |
Jun 10, 2022 MOORE JOHN R |
MOORE JOHN R
General Counsel
|
Sell |
7,125 | $6.05 | 7,125 $6.05 $43,120 |
Jun 09, 2022 MOORE JOHN R |
MOORE JOHN R
General Counsel
|
Sell |
7,615 | $6.49 | 7,615 $6.49 $49,397 |
Jun 08, 2022 MOORE JOHN R |
MOORE JOHN R
General Counsel
|
Sell |
12,566 | $6.63 | 12,566 $6.63 $83,362 |
Jun 07, 2022 MOORE JOHN R |
MOORE JOHN R
General Counsel
|
Sell |
973 | $6.61 | 973 $6.61 $6,427 |
Jun 07, 2022 MOORE JOHN R |
MOORE JOHN R
General Counsel
|
Sell |
17,150 | $6.61 | 17,150 $6.61 $113,276 |
Jun 06, 2022 MOORE JOHN R |
MOORE JOHN R
General Counsel
|
Sell |
13,934 | $6.03 | 13,934 $6.03 $84,085 |
Jun 03, 2022 MOORE JOHN R |
MOORE JOHN R
General Counsel
|
Sell |
15,230 | $6.05 | 15,230 $6.05 $92,198 |
May 18, 2022 ORBIMED ADVISORS LLC |
ORBIMED ADVISORS LLC
|
Buy |
138,000 | $7.21 | 138,000 $7.21 $994,980 |
May 16, 2022 MOORE JOHN R |
MOORE JOHN R
General Counsel
|
Sell |
10,800 | $7.42 | 10,800 $7.42 $80,146 |
Nov 15, 2021 Russell Alan J |
Russell Alan J
Chief Scientific Officer
|
Sell |
441 | $19.07 | 441 $19.07 $8,410 |
Nov 15, 2021 Russell Alan J |
Russell Alan J
Chief Scientific Officer
|
Sell |
38 | $19.61 | 38 $19.61 $745 |
Nov 12, 2021 Russell Alan J |
Russell Alan J
Chief Scientific Officer
|
Sell |
8,562 | $19.51 | 8,562 $19.51 $167,074 |
Nov 11, 2021 Russell Alan J |
Russell Alan J
Chief Scientific Officer
|
Sell |
15,595 | $19.82 | 15,595 $19.82 $309,043 |
Nov 11, 2021 Russell Alan J |
Russell Alan J
Chief Scientific Officer
|
Sell |
3,681 | $20.43 | 3,681 $20.43 $75,195 |
Nov 10, 2021 Russell Alan J |
Russell Alan J
Chief Scientific Officer
|
Sell |
11,746 | $19.70 | 11,746 $19.70 $231,447 |
Nov 10, 2021 Russell Alan J |
Russell Alan J
Chief Scientific Officer
|
Sell |
580 | $20.21 | 580 $20.21 $11,723 |
Nov 09, 2021 Russell Alan J |
Russell Alan J
Chief Scientific Officer
|
Sell |
16,864 | $19.94 | 16,864 $19.94 $336,275 |
Nov 09, 2021 Russell Alan J |
Russell Alan J
Chief Scientific Officer
|
Sell |
12,712 | $20.30 | 12,712 $20.30 $258,031 |
Nov 08, 2021 Russell Alan J |
Russell Alan J
Chief Scientific Officer
|
Sell |
9,017 | $20.16 | 9,017 $20.16 $181,824 |
Nov 05, 2021 Russell Alan J |
Russell Alan J
Chief Scientific Officer
|
Sell |
6 | $20.70 | 6 $20.70 $124 |
Nov 05, 2021 Russell Alan J |
Russell Alan J
Chief Scientific Officer
|
Sell |
13,036 | $19.62 | 13,036 $19.62 $255,783 |
Nov 04, 2021 Russell Alan J |
Russell Alan J
Chief Scientific Officer
|
Sell |
7,392 | $19.76 | 7,392 $19.76 $146,092 |
Nov 03, 2021 Russell Alan J |
Russell Alan J
Chief Scientific Officer
|
Sell |
20,822 | $17.98 | 20,822 $17.98 $374,425 |
Nov 03, 2021 Russell Alan J |
Russell Alan J
Chief Scientific Officer
|
Sell |
4,243 | $18.84 | 4,243 $18.84 $79,944 |
Nov 03, 2021 Russell Alan J |
Russell Alan J
Chief Scientific Officer
|
Sell |
1,119 | $19.42 | 1,119 $19.42 $21,726 |
Nov 02, 2021 Russell Alan J |
Russell Alan J
Chief Scientific Officer
|
Sell |
17,519 | $17.43 | 17,519 $17.43 $305,360 |
Nov 01, 2021 Russell Alan J |
Russell Alan J
Chief Scientific Officer
|
Sell |
469 | $18.02 | 469 $18.02 $8,454 |
Oct 15, 2021 Russell Alan J |
Russell Alan J
Chief Scientific Officer
|
Sell |
1,307 | $18.13 | 1,307 $18.13 $23,698 |
Oct 15, 2021 Russell Alan J |
Russell Alan J
Chief Scientific Officer
|
Sell |
126 | $18.00 | 126 $18.00 $2,268 |
Oct 14, 2021 Russell Alan J |
Russell Alan J
Chief Scientific Officer
|
Sell |
5,749 | $18.18 | 5,749 $18.18 $104,517 |
Oct 11, 2021 Russell Alan J |
Russell Alan J
Chief Scientific Officer
|
Sell |
1,270 | $18.02 | 1,270 $18.02 $22,885 |
Oct 08, 2021 Russell Alan J |
Russell Alan J
Chief Scientific Officer
|
Sell |
5,902 | $18.15 | 5,902 $18.15 $107,121 |
Oct 07, 2021 Russell Alan J |
Russell Alan J
Chief Scientific Officer
|
Sell |
13,018 | $18.56 | 13,018 $18.56 $241,614 |
Oct 06, 2021 Russell Alan J |
Russell Alan J
Chief Scientific Officer
|
Sell |
2,108 | $18.03 | 2,108 $18.03 $38,007 |
Oct 05, 2021 Russell Alan J |
Russell Alan J
Chief Scientific Officer
|
Sell |
5,404 | $18.26 | 5,404 $18.26 $98,677 |
Oct 04, 2021 Russell Alan J |
Russell Alan J
Chief Scientific Officer
|
Sell |
100 | $18.00 | 100 $18.00 $1,800 |
Oct 01, 2021 Russell Alan J |
Russell Alan J
Chief Scientific Officer
|
Sell |
274 | $18.00 | 274 $18.00 $4,932 |
Sep 29, 2021 Russell Alan J |
Russell Alan J
Chief Scientific Officer
|
Sell |
11,226 | $16.83 | 11,226 $16.83 $188,934 |
Sep 29, 2021 Russell Alan J |
Russell Alan J
Chief Scientific Officer
|
Sell |
618 | $17.47 | 618 $17.47 $10,796 |
Sep 28, 2021 Russell Alan J |
Russell Alan J
Chief Scientific Officer
|
Sell |
14,610 | $17.30 | 14,610 $17.30 $252,753 |
Sep 27, 2021 Russell Alan J |
Russell Alan J
Chief Scientific Officer
|
Sell |
11,594 | $17.98 | 11,594 $17.98 $208,460 |
Sep 27, 2021 Russell Alan J |
Russell Alan J
Chief Scientific Officer
|
Sell |
17 | $18.48 | 17 $18.48 $314 |
Sep 24, 2021 Russell Alan J |
Russell Alan J
Chief Scientific Officer
|
Sell |
20,100 | $18.16 | 20,100 $18.16 $365,016 |
Sep 23, 2021 Russell Alan J |
Russell Alan J
Chief Scientific Officer
|
Sell |
21,763 | $18.34 | 21,763 $18.34 $399,133 |
Sep 23, 2021 Russell Alan J |
Russell Alan J
Chief Scientific Officer
|
Sell |
5,072 | $19.42 | 5,072 $19.42 $98,498 |
Mar 30, 2021 Flynn James E |
Flynn James E
|
Buy |
625,000 | $16.00 | 625,000 $16.00 $10,000,000 |
Mar 30, 2021 ORBIMED ADVISORS LLC |
ORBIMED ADVISORS LLC
|
Buy |
46,875 | $16.00 | 46,875 $16.00 $750,000 |
Mar 30, 2021 ORBIMED ADVISORS LLC |
ORBIMED ADVISORS LLC
|
Buy |
312,500 | $16.00 | 312,500 $16.00 $5,000,000 |
Mar 30, 2021 Thompson Peter A. |
Thompson Peter A.
|
Buy |
46,875 | $16.00 | 46,875 $16.00 $750,000 |
Mar 30, 2021 Thompson Peter A. |
Thompson Peter A.
|
Buy |
312,500 | $16.00 | 312,500 $16.00 $5,000,000 |
Mar 30, 2021 ROOT JONATHAN D |
ROOT JONATHAN D
|
Buy |
15,625 | $16.00 | 15,625 $16.00 $250,000 |
Mar 30, 2021 Novo Holdings A/S |
Novo Holdings A/S
|
Buy |
625,000 | $16.00 | 625,000 $16.00 $10,000,000 |
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