Overview

Basic information

Litigation

Active legal matters

Material Events

8-K disclosures

SEC Filings

Key regulatory docs

Insider Transactions

Ownership changes

Overview

Basic information

Litigation

Active legal matters

Material Events

8-K disclosures

SEC Filings

Key regulatory docs

Insider Transactions

Ownership changes

Historical Insider Transactions

The table below lists insider purchases and sales reported by company officers, directors, and major shareholders during the last 12 months.

DATE

INSIDER

INSIDER TYPE SHARES PRICE

SHARES

PRICE

VALUE

May 01, 2025

Meyer Andrew Hollman

Meyer Andrew Hollman
CBO
Sell
2,933 $31.95

2,933

$31.95

$93,703

May 01, 2025

Meyer Andrew Hollman

Meyer Andrew Hollman
CBO
Sell
400 $32.60

400

$32.60

$13,041

Apr 21, 2025

Meyer Andrew Hollman

Meyer Andrew Hollman
CBO
Sell
3,334 $30.00

3,334

$30.00

$100,020

Mar 07, 2025

RA CAPITAL MANAGEMENT, L.P.

RA CAPITAL MANAGEMENT, L.P.
Buy
110,206 $31.02

110,206

$31.02

$3,418,590

Mar 06, 2025

RA CAPITAL MANAGEMENT, L.P.

RA CAPITAL MANAGEMENT, L.P.
Buy
372,093 $30.78

372,093

$30.78

$11,453,023

Mar 05, 2025

RA CAPITAL MANAGEMENT, L.P.

RA CAPITAL MANAGEMENT, L.P.
Buy
304,287 $30.56

304,287

$30.56

$9,299,011

Mar 05, 2025

RA CAPITAL MANAGEMENT, L.P.

RA CAPITAL MANAGEMENT, L.P.
Buy
37,455 $31.30

37,455

$31.30

$1,172,342

Mar 03, 2025

Meyer Andrew Hollman

Meyer Andrew Hollman
CBO
Sell
2,433 $31.88

2,433

$31.88

$77,576

Mar 03, 2025

Meyer Andrew Hollman

Meyer Andrew Hollman
CBO
Sell
901 $32.85

901

$32.85

$29,599

Jan 07, 2025

Campbell David Alan

Campbell David Alan
President and CEO
Sell
5,000 $60.00

5,000

$60.00

$300,004

Jan 02, 2025

Meyer Andrew Hollman

Meyer Andrew Hollman
CBO
Sell
2,922 $53.76

2,922

$53.76

$157,081

Jan 02, 2025

Meyer Andrew Hollman

Meyer Andrew Hollman
CBO
Sell
5,768 $54.51

5,768

$54.51

$314,420

Jan 02, 2025

Meyer Andrew Hollman

Meyer Andrew Hollman
CBO
Sell
3,444 $55.76

3,444

$55.76

$192,033

Jan 02, 2025

Meyer Andrew Hollman

Meyer Andrew Hollman
CBO
Sell
1,000 $56.78

1,000

$56.78

$56,778

Jan 02, 2025

Meyer Andrew Hollman

Meyer Andrew Hollman
CBO
Sell
200 $57.37

200

$57.37

$11,473

Dec 24, 2024

Campbell David Alan

Campbell David Alan
President and CEO
Sell
25,000 $56.19

25,000

$56.19

$1,404,805

Dec 03, 2024

Campbell David Alan

Campbell David Alan
President and CEO
Sell
15,000 $67.00

15,000

$67.00

$1,005,000

Nov 25, 2024

Campbell David Alan

Campbell David Alan
President and CEO
Sell
18,281 $51.43

18,281

$51.43

$940,232

Nov 25, 2024

Campbell David Alan

Campbell David Alan
President and CEO
Sell
6,719 $52.04

6,719

$52.04

$349,647

Oct 28, 2024

Campbell David Alan

Campbell David Alan
President and CEO
Sell
13,897 $53.22

13,897

$53.22

$739,650

Oct 28, 2024

Campbell David Alan

Campbell David Alan
President and CEO
Sell
11,103 $53.94

11,103

$53.94

$598,909

Oct 18, 2024

RA CAPITAL MANAGEMENT, L.P.

RA CAPITAL MANAGEMENT, L.P.
Buy
1,200,000 $44.75

1,200,000

$44.75

$53,700,000

Oct 18, 2024

Avalon Ventures XI, L.P.

Avalon Ventures XI, L.P.
Sell
102,732 $50.30

102,732

$50.30

$5,167,420

Oct 18, 2024

Avalon Ventures XI, L.P.

Avalon Ventures XI, L.P.
Sell
19,900 $50.30

19,900

$50.30

$1,000,970

Oct 18, 2024

Avalon Ventures XI, L.P.

Avalon Ventures XI, L.P.
Sell
104,892 $50.30

104,892

$50.30

$5,276,068

Oct 18, 2024

Avalon Ventures XI, L.P.

Avalon Ventures XI, L.P.
Sell
15,462 $51.18

15,462

$51.18

$791,345

Oct 18, 2024

Avalon Ventures XI, L.P.

Avalon Ventures XI, L.P.
Sell
2,995 $51.18

2,995

$51.18

$153,284

Oct 18, 2024

Avalon Ventures XI, L.P.

Avalon Ventures XI, L.P.
Sell
15,788 $51.18

15,788

$51.18

$808,030

Oct 18, 2024

Avalon Ventures XI, L.P.

Avalon Ventures XI, L.P.
Sell
541,824 $44.75

541,824

$44.75

$24,246,624

Oct 18, 2024

Avalon Ventures XI, L.P.

Avalon Ventures XI, L.P.
Sell
104,957 $44.75

104,957

$44.75

$4,696,826

Oct 18, 2024

Avalon Ventures XI, L.P.

Avalon Ventures XI, L.P.
Sell
553,219 $44.75

553,219

$44.75

$24,756,550

Oct 17, 2024

Avalon Ventures XI, L.P.

Avalon Ventures XI, L.P.
Sell
1,843 $50.02

1,843

$50.02

$92,187

Oct 16, 2024

Avalon Ventures XI, L.P.

Avalon Ventures XI, L.P.
Sell
60,179 $49.69

60,179

$49.69

$2,990,295

Oct 16, 2024

Avalon Ventures XI, L.P.

Avalon Ventures XI, L.P.
Sell
11,657 $49.69

11,657

$49.69

$579,236

Oct 16, 2024

Avalon Ventures XI, L.P.

Avalon Ventures XI, L.P.
Sell
61,445 $49.69

61,445

$49.69

$3,053,202

Oct 16, 2024

Avalon Ventures XI, L.P.

Avalon Ventures XI, L.P.
Sell
29,474 $50.61

29,474

$50.61

$1,491,679

Oct 16, 2024

Avalon Ventures XI, L.P.

Avalon Ventures XI, L.P.
Sell
5,710 $50.61

5,710

$50.61

$288,983

Oct 16, 2024

Avalon Ventures XI, L.P.

Avalon Ventures XI, L.P.
Sell
30,094 $50.61

30,094

$50.61

$1,523,057

Oct 16, 2024

Avalon Ventures XI, L.P.

Avalon Ventures XI, L.P.
Sell
10,957 $50.80

10,957

$50.80

$556,616

Sep 30, 2024

Avalon Ventures XI, L.P.

Avalon Ventures XI, L.P.
Sell
958 $46.24

958

$46.24

$44,298

Sep 27, 2024

Avalon Ventures XI, L.P.

Avalon Ventures XI, L.P.
Sell
45,894 $46.42

45,894

$46.42

$2,130,399

Sep 27, 2024

Avalon Ventures XI, L.P.

Avalon Ventures XI, L.P.
Sell
8,894 $46.42

8,894

$46.42

$412,859

Sep 27, 2024

Avalon Ventures XI, L.P.

Avalon Ventures XI, L.P.
Sell
46,861 $46.42

46,861

$46.42

$2,175,288

Sep 27, 2024

Avalon Ventures XI, L.P.

Avalon Ventures XI, L.P.
Sell
1,511 $47.74

1,511

$47.74

$72,135

Sep 27, 2024

Avalon Ventures XI, L.P.

Avalon Ventures XI, L.P.
Sell
293 $47.74

293

$47.74

$13,988

Sep 27, 2024

Avalon Ventures XI, L.P.

Avalon Ventures XI, L.P.
Sell
1,542 $47.74

1,542

$47.74

$73,615

Sep 27, 2024

Avalon Ventures XI, L.P.

Avalon Ventures XI, L.P.
Sell
1,826 $46.19

1,826

$46.19

$84,343

Sep 27, 2024

Meyer Andrew Hollman

Meyer Andrew Hollman
CBO
Sell
50,000 $45.96

50,000

$45.96

$2,297,755

Sep 27, 2024

Campbell David Alan

Campbell David Alan
President and CEO
Sell
18,957 $46.09

18,957

$46.09

$873,715

Sep 27, 2024

Campbell David Alan

Campbell David Alan
President and CEO
Sell
5,248 $46.86

5,248

$46.86

$245,895

Sep 27, 2024

Campbell David Alan

Campbell David Alan
President and CEO
Sell
795 $47.84

795

$47.84

$38,032

Sep 27, 2024

DiRaimondo Thomas

DiRaimondo Thomas
Chief Scientific Officer
Sell
4,325 $46.21

4,325

$46.21

$199,840

Sep 27, 2024

DiRaimondo Thomas

DiRaimondo Thomas
Chief Scientific Officer
Sell
675 $47.22

675

$47.22

$31,877

Sep 26, 2024

Avalon Ventures XI, L.P.

Avalon Ventures XI, L.P.
Sell
49,497 $46.78

49,497

$46.78

$2,315,470

Sep 26, 2024

Avalon Ventures XI, L.P.

Avalon Ventures XI, L.P.
Sell
9,592 $46.78

9,592

$46.78

$448,714

Sep 26, 2024

Avalon Ventures XI, L.P.

Avalon Ventures XI, L.P.
Sell
50,539 $46.78

50,539

$46.78

$2,364,214

Sep 26, 2024

Avalon Ventures XI, L.P.

Avalon Ventures XI, L.P.
Sell
40,803 $47.77

40,803

$47.77

$1,949,159

Sep 26, 2024

Avalon Ventures XI, L.P.

Avalon Ventures XI, L.P.
Sell
7,908 $47.77

7,908

$47.77

$377,765

Sep 26, 2024

Avalon Ventures XI, L.P.

Avalon Ventures XI, L.P.
Sell
41,661 $47.77

41,661

$47.77

$1,990,146

Sep 13, 2024

Lichter Jay

Lichter Jay
Sell
3,815 $46.68

3,815

$46.68

$178,084

Sep 12, 2024

Avalon Ventures XI, L.P.

Avalon Ventures XI, L.P.
Sell
158,031 $47.00

158,031

$47.00

$7,427,457

Sep 12, 2024

Avalon Ventures XI, L.P.

Avalon Ventures XI, L.P.
Sell
30,613 $47.00

30,613

$47.00

$1,438,811

Sep 12, 2024

Avalon Ventures XI, L.P.

Avalon Ventures XI, L.P.
Sell
161,356 $47.00

161,356

$47.00

$7,583,732

Sep 10, 2024

Avalon Ventures XI, L.P.

Avalon Ventures XI, L.P.
Sell
11,319 $46.13

11,319

$46.13

$522,145

Sep 10, 2024

Avalon Ventures XI, L.P.

Avalon Ventures XI, L.P.
Sell
2,193 $46.13

2,193

$46.13

$101,163

Sep 10, 2024

Avalon Ventures XI, L.P.

Avalon Ventures XI, L.P.
Sell
11,557 $46.13

11,557

$46.13

$533,124

Sep 10, 2024

Avalon Ventures XI, L.P.

Avalon Ventures XI, L.P.
Sell
34,326 $46.66

34,326

$46.66

$1,601,651

Sep 10, 2024

Avalon Ventures XI, L.P.

Avalon Ventures XI, L.P.
Sell
6,649 $46.66

6,649

$46.66

$310,242

Sep 10, 2024

Avalon Ventures XI, L.P.

Avalon Ventures XI, L.P.
Sell
35,047 $46.66

35,047

$46.66

$1,635,293

Sep 09, 2024

Avalon Ventures XI, L.P.

Avalon Ventures XI, L.P.
Sell
2,182 $42.33

2,182

$42.33

$92,364

Sep 06, 2024

Avalon Ventures XI, L.P.

Avalon Ventures XI, L.P.
Sell
108,365 $42.00

108,365

$42.00

$4,551,330

Sep 06, 2024

Avalon Ventures XI, L.P.

Avalon Ventures XI, L.P.
Sell
20,991 $42.00

20,991

$42.00

$881,622

Sep 06, 2024

Avalon Ventures XI, L.P.

Avalon Ventures XI, L.P.
Sell
110,644 $42.00

110,644

$42.00

$4,647,048

Jun 03, 2024

Lichter Jay

Lichter Jay
Sell
677,279 $54.75

677,279

$54.75

$37,081,025

Jun 03, 2024

Lichter Jay

Lichter Jay
Sell
131,196 $54.75

131,196

$54.75

$7,182,981

Jun 03, 2024

Lichter Jay

Lichter Jay
Sell
691,525 $54.75

691,525

$54.75

$37,860,994

Jun 03, 2024

Reardon Tighe

Reardon Tighe
Acting Chief Financial Officer
Sell
131,196 $54.75

131,196

$54.75

$7,182,981

Jun 03, 2024

Reardon Tighe

Reardon Tighe
Acting Chief Financial Officer
Sell
691,525 $54.75

691,525

$54.75

$37,860,994

Jun 03, 2024

Avalon Ventures XI, L.P.

Avalon Ventures XI, L.P.
Sell
677,279 $54.75

677,279

$54.75

$37,081,025

Jun 03, 2024

Avalon Ventures XI, L.P.

Avalon Ventures XI, L.P.
Sell
131,196 $54.75

131,196

$54.75

$7,182,981

Jun 03, 2024

Avalon Ventures XI, L.P.

Avalon Ventures XI, L.P.
Sell
691,525 $54.75

691,525

$54.75

$37,860,994

Nov 13, 2023

Lichter Jay

Lichter Jay
Buy
849,854 $5.87

849,854

$5.87

$4,988,643

Nov 13, 2023

Reardon Tighe

Reardon Tighe
Acting Chief Financial Officer
Buy
849,854 $5.87

849,854

$5.87

$4,988,643

Nov 13, 2023

Avalon Ventures XI, L.P.

Avalon Ventures XI, L.P.
Buy
849,854 $5.87

849,854

$5.87

$4,988,643

Jul 19, 2023

RA CAPITAL MANAGEMENT, L.P.

RA CAPITAL MANAGEMENT, L.P.
Buy
495,008 $12.46

495,008

$12.46

$6,167,800

Jul 19, 2023

RA CAPITAL MANAGEMENT, L.P.

RA CAPITAL MANAGEMENT, L.P.
Buy
503,226 $12.46

503,226

$12.46

$0

Dec 29, 2021

ORBIMED ADVISORS LLC

ORBIMED ADVISORS LLC
Sell
36,700 $20.30

36,700

$20.30

$745,010

Dec 29, 2021

ORBIMED ADVISORS LLC

ORBIMED ADVISORS LLC
Sell
3,700 $20.30

3,700

$20.30

$75,110

Dec 29, 2021

Thompson Peter A.

Thompson Peter A.
Sell
36,700 $20.30

36,700

$20.30

$745,010

Dec 29, 2021

Thompson Peter A.

Thompson Peter A.
Sell
3,700 $20.30

3,700

$20.30

$75,110

Dec 21, 2021

ORBIMED ADVISORS LLC

ORBIMED ADVISORS LLC
Sell
108,300 $19.00

108,300

$19.00

$2,057,700

Dec 21, 2021

ORBIMED ADVISORS LLC

ORBIMED ADVISORS LLC
Sell
11,100 $19.00

11,100

$19.00

$210,900

Dec 21, 2021

Thompson Peter A.

Thompson Peter A.
Sell
108,300 $19.00

108,300

$19.00

$2,057,700

Dec 21, 2021

Thompson Peter A.

Thompson Peter A.
Sell
11,100 $19.00

11,100

$19.00

$210,900

Jun 15, 2021

ORBIMED ADVISORS LLC

ORBIMED ADVISORS LLC
Buy
588,203 $17.00

588,203

$17.00

$9,999,451

Jun 15, 2021

ORBIMED ADVISORS LLC

ORBIMED ADVISORS LLC
Buy
117,650 $17.00

117,650

$17.00

$2,000,050

Jun 15, 2021

Thompson Peter A.

Thompson Peter A.
Buy
588,203 $17.00

588,203

$17.00

$9,999,451

Jun 15, 2021

Thompson Peter A.

Thompson Peter A.
Buy
117,650 $17.00

117,650

$17.00

$2,000,050

Jun 15, 2021

Lichter Jay

Lichter Jay
Buy
629,411 $17.00

629,411

$17.00

$10,699,987

Jun 15, 2021

RA CAPITAL MANAGEMENT, L.P.

RA CAPITAL MANAGEMENT, L.P.
Buy
2,752,190 $17.00

2,752,190

$17.00

$46,787,230

Jun 15, 2021

RA CAPITAL MANAGEMENT, L.P.

RA CAPITAL MANAGEMENT, L.P.
Buy
188,986 $17.00

188,986

$17.00

$3,212,762

Jun 15, 2021

Reardon Tighe

Reardon Tighe
Acting Chief Financial Officer
Buy
629,411 $17.00

629,411

$17.00

$10,699,987

Jun 15, 2021

Bregua Corp

Bregua Corp
Buy
58,823 $17.00

58,823

$17.00

$999,991

Jun 15, 2021

Avalon Ventures XI, L.P.

Avalon Ventures XI, L.P.
Buy
629,411 $17.00

629,411

$17.00

$10,699,987

TOP