Overview

Basic information

Litigation

Active legal matters

Material Events

8-K disclosures

SEC Filings

Key regulatory docs

Insider Transactions

Ownership changes

Overview

Basic information

Litigation

Active legal matters

Material Events

8-K disclosures

SEC Filings

Key regulatory docs

Insider Transactions

Ownership changes

Historical Insider Transactions

The table below lists insider purchases and sales reported by company officers, directors, and major shareholders during the last 12 months.

DATE

INSIDER

INSIDER TYPE SHARES PRICE

SHARES

PRICE

VALUE

Aug 22, 2025

Verdine Gregory L.

Verdine Gregory L.
Sell
10,000 $10.00

10,000

$10.00

$100,000

Aug 22, 2025

BOLNO PAUL

BOLNO PAUL
President and CEO
Sell
217,351 $10.10

217,351

$10.10

$2,194,810

Aug 15, 2025

Tan Aik Na

Tan Aik Na
Sell
21,000 $9.25

21,000

$9.25

$194,250

Aug 13, 2025

HENRY CHRISTIAN O

HENRY CHRISTIAN O
Sell
9,670 $8.81

9,670

$8.81

$85,193

Aug 05, 2025

Tan Aik Na

Tan Aik Na
Sell
1,127 $8.75

1,127

$8.75

$9,861

Aug 05, 2025

TAKANASHI KEN

TAKANASHI KEN
Sell
4,872 $8.75

4,872

$8.75

$42,630

Jun 13, 2025

Verdine Gregory L.

Verdine Gregory L.
Sell
30,000 $6.95

30,000

$6.95

$208,500

Mar 20, 2025

HENRY CHRISTIAN O

HENRY CHRISTIAN O
Sell
10,500 $9.77

10,500

$9.77

$102,575

Mar 07, 2025

BOLNO PAUL

BOLNO PAUL
President and CEO
Sell
169,025 $9.57

169,025

$9.57

$1,617,569

Nov 25, 2024

BOLNO PAUL

BOLNO PAUL
President and CEO
Sell
50,000 $15.00

50,000

$15.00

$750,000

Nov 15, 2024

BOLNO PAUL

BOLNO PAUL
President and CEO
Sell
51,234 $14.32

51,234

$14.32

$733,671

Nov 08, 2024

Francis Chris

Francis Chris
See Remarks
Sell
36,000 $16.00

36,000

$16.00

$576,000

Oct 16, 2024

BOLNO PAUL

BOLNO PAUL
President and CEO
Sell
90,474 $15.00

90,474

$15.00

$1,357,110

Oct 16, 2024

Francis Chris

Francis Chris
See Remarks
Sell
22,500 $13.50

22,500

$13.50

$303,750

Oct 16, 2024

Francis Chris

Francis Chris
See Remarks
Sell
65,625 $13.75

65,625

$13.75

$902,344

Oct 16, 2024

Francis Chris

Francis Chris
See Remarks
Sell
40,997 $13.00

40,997

$13.00

$532,961

Oct 16, 2024

Francis Chris

Francis Chris
See Remarks
Sell
79,714 $14.00

79,714

$14.00

$1,115,996

Sep 27, 2024

GLAXOSMITHKLINE PLC

GLAXOSMITHKLINE PLC
Buy
2,791,930 $8.00

2,791,930

$8.00

$22,335,440

Sep 25, 2024

Moran Kyle

Moran Kyle
CFO
Sell
17,146 $9.00

17,146

$9.00

$154,314

Aug 21, 2024

BOLNO PAUL

BOLNO PAUL
President and CEO
Sell
48,366 $5.78

48,366

$5.78

$279,555

Apr 03, 2024

Moran Kyle

Moran Kyle
CFO
Sell
15,630 $6.17

15,630

$6.17

$96,421

Dec 11, 2023

RA CAPITAL MANAGEMENT, L.P.

RA CAPITAL MANAGEMENT, L.P.
Buy
1,000,000 $5.00

1,000,000

$5.00

$5,000,000

Dec 07, 2023

GLAXOSMITHKLINE PLC

GLAXOSMITHKLINE PLC
Buy
3,300,000 $5.00

3,300,000

$5.00

$16,500,000

Aug 23, 2023

Moran Kyle

Moran Kyle
CFO
Sell
37,062 $4.75

37,062

$4.75

$176,119

Feb 16, 2023

Moran Kyle

Moran Kyle
CFO
Sell
9,729 $4.04

9,729

$4.04

$39,305

Feb 16, 2023

Vargeese Chandra

Vargeese Chandra
See Remarks
Sell
10,249 $4.03

10,249

$4.03

$41,303

Feb 16, 2023

BOLNO PAUL

BOLNO PAUL
President and CEO
Sell
29,400 $4.04

29,400

$4.04

$118,776

Feb 16, 2023

Francis Chris

Francis Chris
See Remarks
Sell
10,258 $4.03

10,258

$4.03

$41,340

Jun 16, 2022

RA CAPITAL MANAGEMENT, L.P.

RA CAPITAL MANAGEMENT, L.P.
Buy
7,093,656 $2.15

7,093,656

$2.15

$0

Jun 16, 2022

RA CAPITAL MANAGEMENT, L.P.

RA CAPITAL MANAGEMENT, L.P.
Buy
9,480,052 $2.15

9,480,052

$2.15

$20,382,112

May 05, 2022

Moran Kyle

Moran Kyle
CFO
Sell
5,021 $1.72

5,021

$1.72

$8,636

May 05, 2022

Vargeese Chandra

Vargeese Chandra
See Remarks
Sell
16,714 $1.72

16,714

$1.72

$28,748

May 05, 2022

Panzara Michael A.

Panzara Michael A.
See Remarks
Sell
16,714 $1.72

16,714

$1.72

$28,748

May 05, 2022

BOLNO PAUL

BOLNO PAUL
President and CEO
Sell
33,501 $1.72

33,501

$1.72

$57,622

May 05, 2022

Francis Chris

Francis Chris
See Remarks
Sell
10,867 $1.72

10,867

$1.72

$18,691

Feb 16, 2022

Panzara Michael A.

Panzara Michael A.
See Remarks
Sell
10,603 $2.31

10,603

$2.31

$24,493

Feb 16, 2022

Vargeese Chandra

Vargeese Chandra
CTO
Sell
10,603 $2.32

10,603

$2.32

$24,599

Feb 16, 2022

BOLNO PAUL

BOLNO PAUL
President and CEO
Sell
33,150 $2.32

33,150

$2.32

$76,908

Feb 16, 2022

Francis Chris

Francis Chris
See Remarks
Sell
10,123 $2.31

10,123

$2.31

$23,384

Feb 16, 2022

Moran Kyle

Moran Kyle
CFO
Sell
9,204 $2.31

9,204

$2.31

$21,261

Feb 16, 2021

BOLNO PAUL

BOLNO PAUL
President and CEO
Sell
11,205 $10.57

11,205

$10.57

$118,437

Feb 16, 2021

Moran Kyle

Moran Kyle
CFO
Sell
1,722 $10.57

1,722

$10.57

$18,202

Feb 16, 2021

Vargeese Chandra

Vargeese Chandra
CTO
Sell
3,145 $10.57

3,145

$10.57

$33,243

Feb 16, 2021

Francis Chris

Francis Chris
See Remarks
Sell
2,698 $10.57

2,698

$10.57

$28,518

Feb 16, 2021

Panzara Michael A.

Panzara Michael A.
See Remarks
Sell
2,929 $10.57

2,929

$10.57

$30,960

Sep 15, 2020

BOLNO PAUL

BOLNO PAUL
President and CEO
Sell
100,000 $15.00

100,000

$15.00

$1,500,000

Aug 25, 2020

BOLNO PAUL

BOLNO PAUL
President and CEO
Sell
25,000 $12.00

25,000

$12.00

$300,000

Jul 02, 2020

BOLNO PAUL

BOLNO PAUL
President and CEO
Sell
4,509 $10.82

4,509

$10.82

$48,787

Jul 02, 2020

BOLNO PAUL

BOLNO PAUL
President and CEO
Sell
43,068 $10.26

43,068

$10.26

$441,878

Jul 02, 2020

BOLNO PAUL

BOLNO PAUL
President and CEO
Sell
4,079 $10.91

4,079

$10.91

$44,502

Jul 02, 2020

BOLNO PAUL

BOLNO PAUL
President and CEO
Sell
95,921 $10.27

95,921

$10.27

$985,109

Feb 18, 2020

Francis Chris

Francis Chris
See Remarks
Sell
2,708 $7.85

2,708

$7.85

$21,258

Feb 18, 2020

Vargeese Chandra

Vargeese Chandra
Senior VP, Drug Discovery
Sell
3,188 $7.85

3,188

$7.85

$25,026

Feb 18, 2020

BOLNO PAUL

BOLNO PAUL
President and CEO
Sell
11,451 $7.85

11,451

$7.85

$89,890

Feb 18, 2020

Panzara Michael A.

Panzara Michael A.
CMO
Sell
2,981 $7.85

2,981

$7.85

$23,401

Feb 03, 2020

Gaiero David G

Gaiero David G
Interim CFO
Sell
651 $7.00

651

$7.00

$4,557

Dec 03, 2019

Vargeese Chandra

Vargeese Chandra
Senior VP, Drug Discovery
Sell
6,000 $35.00

6,000

$35.00

$210,000

Nov 20, 2019

Verdine Gregory L.

Verdine Gregory L.
Sell
3,400 $31.59

3,400

$31.59

$107,406

Nov 20, 2019

Verdine Gregory L.

Verdine Gregory L.
Sell
24,030 $30.27

24,030

$30.27

$727,388

Nov 20, 2019

Verdine Gregory L.

Verdine Gregory L.
Sell
2,609 $32.74

2,609

$32.74

$85,419

Jul 05, 2019

Panzara Michael A.

Panzara Michael A.
CMO
Sell
445 $27.26

445

$27.26

$12,131

Jul 05, 2019

Panzara Michael A.

Panzara Michael A.
CMO
Sell
2,613 $26.88

2,613

$26.88

$70,237

Mar 15, 2019

BOLNO PAUL

BOLNO PAUL
President and CEO
Sell
34,935 $45.45

34,935

$45.45

$1,587,796

Mar 15, 2019

BOLNO PAUL

BOLNO PAUL
President and CEO
Sell
8,237 $45.22

8,237

$45.22

$372,477

Mar 15, 2019

BOLNO PAUL

BOLNO PAUL
President and CEO
Sell
5,065 $45.89

5,065

$45.89

$232,433

Mar 15, 2019

BOLNO PAUL

BOLNO PAUL
President and CEO
Sell
1,763 $46.00

1,763

$46.00

$81,098

Mar 11, 2019

Panzara Michael A.

Panzara Michael A.
Franchise Lead, Neurology
Sell
7,000 $48.00

7,000

$48.00

$336,000

Feb 19, 2019

BOLNO PAUL

BOLNO PAUL
President and CEO
Sell
119 $37.47

119

$37.47

$4,458

Feb 19, 2019

Francis Chris

Francis Chris
See Remarks
Sell
1,709 $36.84

1,709

$36.84

$62,959

Feb 19, 2019

Vargeese Chandra

Vargeese Chandra
Senior VP, Drug Discovery
Sell
2,055 $36.84

2,055

$36.84

$75,706

Feb 19, 2019

BOLNO PAUL

BOLNO PAUL
President and CEO
Sell
7,614 $36.38

7,614

$36.38

$276,997

Feb 19, 2019

Regnante Keith

Regnante Keith
CFO
Sell
1,298 $36.84

1,298

$36.84

$47,818

Feb 19, 2019

Panzara Michael A.

Panzara Michael A.
Franchise Lead, Neurology
Sell
1,837 $36.84

1,837

$36.84

$67,674

Jan 24, 2019

RA CAPITAL MANAGEMENT, L.P.

RA CAPITAL MANAGEMENT, L.P.
Buy
263,158 $38.00

263,158

$38.00

$10,000,004

Nov 14, 2018

Verdine Gregory L.

Verdine Gregory L.
Sell
10,700 $38.59

10,700

$38.59

$412,913

Nov 14, 2018

Verdine Gregory L.

Verdine Gregory L.
Sell
4,300 $39.52

4,300

$39.52

$169,936

Sep 25, 2018

Francis Chris

Francis Chris
See Remarks
Sell
10,543 $56.00

10,543

$56.00

$590,408

Sep 24, 2018

Vargeese Chandra

Vargeese Chandra
Senior VP, Drug Discovery
Sell
3,000 $55.00

3,000

$55.00

$165,000

Sep 24, 2018

Regnante Keith

Regnante Keith
CFO
Sell
29,500 $55.00

29,500

$55.00

$1,622,500

Sep 24, 2018

Francis Chris

Francis Chris
See Remarks
Sell
1,032 $56.00

1,032

$56.00

$57,792

Jul 09, 2018

Francis Chris

Francis Chris
See Remarks
Sell
596 $38.22

596

$38.22

$22,779

Jul 09, 2018

Francis Chris

Francis Chris
See Remarks
Sell
23,900 $37.25

23,900

$37.25

$890,275

Jun 01, 2018

Francis Chris

Francis Chris
See Remarks
Sell
24,496 $48.00

24,496

$48.00

$1,175,808

May 30, 2018

Francis Chris

Francis Chris
See Remarks
Sell
24,496 $45.50

24,496

$45.50

$1,114,568

May 30, 2018

BOLNO PAUL

BOLNO PAUL
President and CEO
Sell
20,250 $45.00

20,250

$45.00

$911,250

May 29, 2018

BOLNO PAUL

BOLNO PAUL
President and CEO
Sell
3,145 $45.00

3,145

$45.00

$141,525

May 25, 2018

BOLNO PAUL

BOLNO PAUL
President and CEO
Sell
8,316 $45.00

8,316

$45.00

$374,220

May 02, 2018

BOLNO PAUL

BOLNO PAUL
President and CEO
Sell
18,289 $45.00

18,289

$45.00

$823,005

Feb 20, 2018

Francis Chris

Francis Chris
See Remarks
Sell
11,504 $55.95

11,504

$55.95

$643,649

Feb 16, 2018

Regnante Keith

Regnante Keith
CFO
Sell
316 $51.85

316

$51.85

$16,385

Feb 16, 2018

BOLNO PAUL

BOLNO PAUL
President and CEO
Sell
2,200 $51.62

2,200

$51.62

$113,564

Feb 16, 2018

BOLNO PAUL

BOLNO PAUL
President and CEO
Sell
514 $51.01

514

$51.01

$26,219

Feb 16, 2018

Francis Chris

Francis Chris
See Remarks
Sell
9,412 $55.00

9,412

$55.00

$517,660

Feb 16, 2018

Francis Chris

Francis Chris
See Remarks
Sell
723 $51.80

723

$51.80

$37,451

Feb 16, 2018

Panzara Michael A.

Panzara Michael A.
Franchise Lead, Neurology
Sell
511 $52.10

511

$52.10

$26,623

Feb 15, 2018

Panzara Michael A.

Panzara Michael A.
Franchise Lead, Neurology
Sell
18,750 $50.00

18,750

$50.00

$937,500

Feb 15, 2018

Vargeese Chandra

Vargeese Chandra
See Remarks
Sell
2,000 $50.00

2,000

$50.00

$100,000

Jan 23, 2018

Vargeese Chandra

Vargeese Chandra
See Remarks
Sell
2,000 $40.00

2,000

$40.00

$80,000

TOP